Buffered Cortisol Response to Stress in Patients With Epilepsy and Its Association With Memory and Quality of Life

Patients with epilepsy may exhibit a buffered cortisol response to acute stress. Preservation of this response is associated with better clinical, cognitive, and QOL outcomes. Despite limitations such as the cross-sectional design and sample specificity, these findings could help clarify the underlying mechanisms of stress-epilepsy interaction.

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Publication Details

Journal
Neurology
Published
2025-09-16
DOI
https://doi.org/10.1212/wnl.0000000000214103
Primary Topic
Stress Responses and Cortisol
Type
article
Field-Weighted Citation Impact
0.00
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article

Buffered Cortisol Response to Stress in Patients With Epilepsy and Its Association With Memory and Quality of Life

Vicente Villanueva, Alicia Salvador, Alejandro Lozano‐García, Esperanza González‐Bono et al.
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Buffered Cortisol Response to Stress in Patients With Epilepsy and Its Association With Memory and Quality of Life

Vicente Villanueva, Alicia Salvador, Alejandro Lozano‐García, Esperanza González‐Bono, Kevin Gil Hampel, Irene Cano‐López, Judit Catalán‐Aguilar, Paula Tormos‐Pons
article en

Abstract

Patients with epilepsy may exhibit a buffered cortisol response to acute stress. Preservation of this response is associated with better clinical, cognitive, and QOL outcomes. Despite limitations such as the cross-sectional design and sample specificity, these findings could help clarify the underlying mechanisms of stress-epilepsy interaction.

NeurologyVol. 105(7)
Universidad de Zaragoza (ES), Valencian International University (ES), Hospital Universitari i Politècnic La Fe (ES), Centre d’Investigació i Desenvolupament (ES)
Openalex Percentile: Top 74%
Stress Responses and Cortisol
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