On a continuum model for random genetic drift: a dynamic boundary condition approach
We propose a new continuum model for random genetic drift by employing a dynamic boundary condition approach. The model can be viewed as a regularized version of the Kimura equation and admits a continuous solution. We establish existence and uniqueness of a strong solution to the regularized system. Numerical experiments illustrate that, for sufficiently small regularization parameters, the model can capture key phenomena of the original Kimura equation, such as gene fixation and conservation of the first moment.
Authors
- Jan-Eric Sulzbach (ORCID: https://orcid.org/0000-0002-9446-2366)
- Chun Liu (ORCID: https://orcid.org/0000-0002-0480-0107)
- Yiwei Wang (ORCID: https://orcid.org/0000-0002-1267-9669)
Institutions
- University of California, Riverside (US)
- Illinois Institute of Technology (US)
- Technical University of Munich (DE)
Publication Details
- Journal
- Communications in Analysis and Mechanics
- Published
- 2025-01-01
- DOI
- https://doi.org/10.3934/cam.2025033
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 0.00