Heterogeneity of type 2 diabetes in rural India
The use of BMI and simple body composition measures led to the identification of a distinct lean phenotype that is characterized by a low BMI, poor insulin secretion, and the absence of central obesity and adiposity. Further research is warranted to understand the pathophysiology and to develop a personalized therapeutic approach for lean subjects with type 2 diabetes. It is time to reconsider the glucocentric, one-size-fits-all approach for type 2 diabetes treatment.
Authors
- Shreyansh Deosale
- Ajay B. Patil (ORCID: https://orcid.org/0000-0003-0509-4926)
- Suvarna Patil (ORCID: https://orcid.org/0000-0002-9564-986X)
- Sachin Surnar
- Avinash S. Kumbhar (ORCID: https://orcid.org/0000-0002-2087-4827)
- Kaustubh H Tare
- Dnyaneshwar Jadhav
- Charudatta Joglekar (ORCID: https://orcid.org/0000-0002-2193-393X)
- Pallavi Bhat (ORCID: https://orcid.org/0009-0002-3223-6950)
- Aniket Khaladkar
- Tushar Humbare
- Datta Mulay
- Vaibhav Methi
Institutions
- B. J. Medical College & Sassoon Hospital (IN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-09-09
- DOI
- https://doi.org/10.3389/fendo.2025.1524194
- Citations
- 2
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 2.59