Evaluation of the feasibility, safety, and preliminary effectiveness of hyperthermic intraperitoneal chemotherapy following radical surgery for locally advanced gastric cancer
In this real-world dual-center study, HIPEC following D2 surgery was found to be feasible and safe, and was associated with a reduced risk of peritoneal recurrence in patients with locally advanced gastric cancer. These observational findings warrant further validation in randomized controlled trials.
Authors
- Hang Yu (ORCID: https://orcid.org/0000-0002-7273-3233)
- Jie Chai
- Cheng Zhao (ORCID: https://orcid.org/0000-0001-7205-4196)
- Shijun Zhao (ORCID: https://orcid.org/0000-0001-5554-0336)
- Dehai Wang (ORCID: https://orcid.org/0000-0001-7029-9624)
- Lang Wang (ORCID: https://orcid.org/0000-0003-2608-1593)
- Tianze Zhang
Institutions
- Second Hospital of Shandong University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-09-09
- DOI
- https://doi.org/10.3389/fonc.2025.1498388
- Primary Topic
- Intraperitoneal and Appendiceal Malignancies
- Type
- article
- Field-Weighted Citation Impact
- 0.00