Case Report: Functional MR imaging of alveolar soft part sarcoma

This study presents a rare case of acinar soft tissue sarcoma and provides a detailed analysis of its multi-parameter quantitative functional MRI (fMRI) characteristics. The patient, a 16-year-old male, was diagnosed with acinar soft tissue sarcoma after presenting with a progressively enlarging mass in the right thigh. To determine the extent and nature of the lesion, MRI examinations were performed using conventional plain scans, contrast-enhanced scans, dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), and intravoxel incoherent motion (IVIM) for quantitative analysis. Functional MRI imaging not only provides crucial diagnostic and differential diagnostic information for acinar soft tissue sarcoma, but also reveals through DCE-MRI and IVIM imaging indicators that ASPS exhibits high cellular density, increased vascular permeability, and abundant neovascularization. The local microcirculation characteristics offer vital insights into the tumor's biological behavior and prognosis. Furthermore, functional MRI aids in precise diagnosis while providing references for surgical planning, postoperative adjuvant therapy, long-term follow-up evaluation, and recurrence risk prediction.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-09-09
DOI
https://doi.org/10.3389/fonc.2025.1602577
Primary Topic
Soft tissue tumor case studies
Type
article
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article

Case Report: Functional MR imaging of alveolar soft part sarcoma

Zhaoyang Yang, Jiuming Jiang, Jie Li, Meng Li et al.
Frontiers in Oncology
Soft tissue tumor case studies
article

Case Report: Functional MR imaging of alveolar soft part sarcoma

Zhaoyang Yang, Jiuming Jiang, Jie Li, Meng Li, L H Gong
article en

Abstract

This study presents a rare case of acinar soft tissue sarcoma and provides a detailed analysis of its multi-parameter quantitative functional MRI (fMRI) characteristics. The patient, a 16-year-old male, was diagnosed with acinar soft tissue sarcoma after presenting with a progressively enlarging mass in the right thigh. To determine the extent and nature of the lesion, MRI examinations were performed using conventional plain scans, contrast-enhanced scans, dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), and intravoxel incoherent motion (IVIM) for quantitative analysis. Functional MRI imaging not only provides crucial diagnostic and differential diagnostic information for acinar soft tissue sarcoma, but also reveals through DCE-MRI and IVIM imaging indicators that ASPS exhibits high cellular density, increased vascular permeability, and abundant neovascularization. The local microcirculation characteristics offer vital insights into the tumor's biological behavior and prognosis. Furthermore, functional MRI aids in precise diagnosis while providing references for surgical planning, postoperative adjuvant therapy, long-term follow-up evaluation, and recurrence risk prediction.

Frontiers in OncologyVol. 15
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Shuozhou Central Hospital (CN), National Cancer Center (US)
Openalex Percentile: Top 63%
Soft tissue tumor case studies
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