Atherogenic ApoB-dyslipidemia, atherosclerotic cardiovascular disease, cardiac dysfunction and remodeling in high-risk young women with and without polycystic ovary syndrome: A pilot study
Our pilot results supports the potential of apoB-dyslipidemia, cIMT, carotid plaque height and left ventricular diastolic dysfunction and remodeling to be used in screening for CVD risk in high-risk populations such as overweight-obese women with and without PCOS. ApoB may be useful to predict atherosclerotic vascular burden and progression of cIMT and carotid plaque, and could be used to develop a female specific algorithm for ACVD risk in high-risk young women with and without PCOS.
Authors
- Julette Marie Batara (ORCID: https://orcid.org/0000-0003-2824-4544)
- Paolo Raggi (ORCID: https://orcid.org/0000-0002-5766-1948)
- Mahua Ghosh (ORCID: https://orcid.org/0009-0006-4178-2629)
- Mich Wilke
- Jonathan Windram (ORCID: https://orcid.org/0000-0002-0361-9752)
- Donna F. Vine (ORCID: https://orcid.org/0000-0001-7816-3422)
- Spencer D. Proctor (ORCID: https://orcid.org/0000-0002-7597-5262)
- Melanie Cree‐Green (ORCID: https://orcid.org/0000-0003-1593-1695)
- Harald Becher (ORCID: https://orcid.org/0000-0001-8770-8594)
- Xiaoying Wu (ORCID: https://orcid.org/0000-0002-7913-118X)
Institutions
- University of Alberta (CA)
- Women and Children’s Health Research Institute (CA)
- University of Colorado Anschutz Medical Campus (US)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-09-09
- DOI
- https://doi.org/10.3389/fendo.2025.1520922
- Citations
- 2
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.40
Funders
- Heart and Stroke Foundation of Canada
- Children's Health Research Institute
- Women and Children's Health Research Institute
- Heart Research Institute