Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy
The findings of this study suggest that T0 attenuates sepsis-induced pulmonary injury by promoting macrophage autophagy via suppression of S100A8 expression.
Authors
- Zhi Xu (ORCID: https://orcid.org/0000-0003-1199-6635)
- Liang Guo (ORCID: https://orcid.org/0000-0003-4892-2744)
- Chaowang Huang
- Xueling Wu (ORCID: https://orcid.org/0000-0002-9752-3734)
- Ben Wang (ORCID: https://orcid.org/0000-0002-1191-4591)
- Ran Wang (ORCID: https://orcid.org/0000-0002-3016-1011)
- Zhong Yu
Institutions
- Army Medical University (CN)
- Renji Hospital (CN)
- Daping Hospital (CN)
- Xinqiao Hospital (CN)
- Southwest Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-09-09
- DOI
- https://doi.org/10.3389/fphar.2025.1552034
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Centre Scientifique et Technique du Bâtiment