Correlation Between Microbial Toxin Levels and Biochemical Markers of Organ Damage in ICU Patients

Microbial toxin burden demonstrates a strong association with biochemical evidence of organ injury and disease severity in ICU patients. Combined toxin-biomarker profiling may have prognostic value for identifying high-risk patients, but its clinical application requires validation through larger multicentre studies with serial sampling before widespread adoption.

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Publication Details

Journal
Cureus
Published
2025-09-08
DOI
https://doi.org/10.7759/cureus.91870
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Correlation Between Microbial Toxin Levels and Biochemical Markers of Organ Damage in ICU Patients

S. Sangeeta, Ramesh Kandimalla, Bhagyashree K Bhuyar, Harish Thummala et al.
Cureus
Intensive Care Unit Cognitive Disorders
article

Correlation Between Microbial Toxin Levels and Biochemical Markers of Organ Damage in ICU Patients

S. Sangeeta, Ramesh Kandimalla, Bhagyashree K Bhuyar, Harish Thummala, Likhith Sai Kiran Rapeti
article en

Abstract

Microbial toxin burden demonstrates a strong association with biochemical evidence of organ injury and disease severity in ICU patients. Combined toxin-biomarker profiling may have prognostic value for identifying high-risk patients, but its clinical application requires validation through larger multicentre studies with serial sampling before widespread adoption.

CureusVol. 17(9)
National Archives and Records Administration (US), Government Medical College (IN), Guntur Medical College (IN), Nippon Koei (Japan) (JP), Indian Institute of Management Visakhapatnam (IN)
Openalex Percentile: Top 71%
Intensive Care Unit Cognitive Disorders
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