Sufficient conditions for global boundedness in inertial chemotaxis systems with logistic growth

This paper investigates a chemotaxis model described by the following system of partial differential equations:$ \begin{eqnarray*} \left\{ \begin{array}{llll} u_{t} = \Delta u - \nabla \cdot (u \mathbf{w}) + \gamma(u - u^{\alpha}), & x \in \Omega, \, t > 0, \\ v_{t} = \Delta v - v + u, & x \in \Omega, \, t > 0, \\ \mathbf{w}_{t} = \Delta \mathbf{w} - \mathbf{w} + \chi \nabla v, & x \in \Omega, \, t > 0, \\ \partial_{\mathbf{n}} u = \partial_{\mathbf{n}} v = 0, \quad \mathbf{w} = 0, & x \in \partial \Omega, \end{array} \right. \end{eqnarray*} $posed on a smooth, bounded domain $ \Omega \subset \mathbb{R}^n $, where $ \chi > 0 $, $ \gamma \geq 0 $, and $ \alpha > 1 $ are parameters. By employing $ L^p $-estimates and a carefully constructed bootstrap iteration method, we analyze the intricate mathematical relationships governing the system. Our findings demonstrate the existence of globally bounded solutions for $ n \geq 4 $, contingent upon the conditions that $ \gamma > 0 $ and $ \alpha > \frac{3n + 6}{n + 8} $. These findings significantly refine the known parameter constraints for global solution existence. In particular, our work improves upon previous studies—such as those by Zhang et al. (2019), Dong and Peng (2021), and Mu and Tao (2022)—which typically imposed the stricter condition $ \alpha > \frac{1}{2} + \frac{n}{4} $. Our analysis thus provides sharper criteria for $ \alpha $, broadening the understanding of solution behavior in chemotaxis systems.

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Journal
AIMS Mathematics
Published
2025-01-01
DOI
https://doi.org/10.3934/math.2025921
Primary Topic
Mathematical Biology Tumor Growth
Type
article
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article

Sufficient conditions for global boundedness in inertial chemotaxis systems with logistic growth

Liqiong Pu, Jiashan Zheng
AIMS Mathematics
Mathematical Biology Tumor Growth
article

Sufficient conditions for global boundedness in inertial chemotaxis systems with logistic growth

Liqiong Pu, Jiashan Zheng
article en

Abstract

This paper investigates a chemotaxis model described by the following system of partial differential equations:$ \begin{eqnarray*} \left\{ \begin{array}{llll} u_{t} = \Delta u - \nabla \cdot (u \mathbf{w}) + \gamma(u - u^{\alpha}), & x \in \Omega, \, t > 0, \\ v_{t} = \Delta v - v + u, & x \in \Omega, \, t > 0, \\ \mathbf{w}_{t} = \Delta \mathbf{w} - \mathbf{w} + \chi \nabla v, & x \in \Omega, \, t > 0, \\ \partial_{\mathbf{n}} u = \partial_{\mathbf{n}} v = 0, \quad \mathbf{w} = 0, & x \in \partial \Omega, \end{array} \right. \end{eqnarray*} $posed on a smooth, bounded domain $ \Omega \subset \mathbb{R}^n $, where $ \chi > 0 $, $ \gamma \geq 0 $, and $ \alpha > 1 $ are parameters. By employing $ L^p $-estimates and a carefully constructed bootstrap iteration method, we analyze the intricate mathematical relationships governing the system. Our findings demonstrate the existence of globally bounded solutions for $ n \geq 4 $, contingent upon the conditions that $ \gamma > 0 $ and $ \alpha > \frac{3n + 6}{n + 8} $. These findings significantly refine the known parameter constraints for global solution existence. In particular, our work improves upon previous studies—such as those by Zhang et al. (2019), Dong and Peng (2021), and Mu and Tao (2022)—which typically imposed the stricter condition $ \alpha > \frac{1}{2} + \frac{n}{4} $. Our analysis thus provides sharper criteria for $ \alpha $, broadening the understanding of solution behavior in chemotaxis systems.

AIMS MathematicsVol. 10(9)
Yantai University (CN)
Openalex Percentile: Top 72%
Mathematical Biology Tumor Growth
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