Weakened benefits of ADHD drugs over time reflect broader treated population

A cohort study using Swedish national data has found that while use of medication treatments for attention‐deficit hyperactivity disorder (ADHD) consistently reduced risk of self‐harm, unintentional injury, and other adverse outcomes, these associations weakened in later years of the study. Investigators theorized that higher prescribing rates over time incorporated more individuals with less severe symptoms. Study results were published online June 25, 2025, in JAMA Psychiatry .

Publication Details

Journal
The Brown University Psychopharmacology Update
Published
2025-09-09
DOI
https://doi.org/10.1002/pu.31356
Primary Topic
Attention Deficit Hyperactivity Disorder
Type
article
Field-Weighted Citation Impact
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article

Weakened benefits of ADHD drugs over time reflect broader treated population

The Brown University Psychopharmacology Update
Attention Deficit Hyperactivity Disorder
article

Weakened benefits of ADHD drugs over time reflect broader treated population

article en

Abstract

A cohort study using Swedish national data has found that while use of medication treatments for attention‐deficit hyperactivity disorder (ADHD) consistently reduced risk of self‐harm, unintentional injury, and other adverse outcomes, these associations weakened in later years of the study. Investigators theorized that higher prescribing rates over time incorporated more individuals with less severe symptoms. Study results were published online June 25, 2025, in JAMA Psychiatry .

The Brown University Psychopharmacology UpdateVol. 36(10)
Openalex Percentile: Top 70%
Attention Deficit Hyperactivity Disorder
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Weakened benefits of ADHD drugs over time reflect broader treated population · The Brown University Psychopharmacology Update (2025) | TGRS Research Map | TGRS