Presystolic Wave Evaluation in Patients with Coronary Slow Flow

Background: Noninvasive assessment of arterial stiffness in patients with Coronary Slow Flow Phenomenon (CSFP) could be valuable for evaluating cardiovascular risk. Presystolic Wave (PSW) velocity is considered a predictor of cardiovascular disease and a marker of arterial stiffness. This study aimed to evaluate PSW velocity in patients with CSFP Methods: This cross-sectional study investigated patients with acute coronary syndrome, dividing them into two groups: Cerebrospinal Fluid (CSF) and Coronary Normal Flow (CNF), with 30 patients in each group. Both groups underwent echocardiography, and PSW velocity was compared between them. Data analysis was performed using SPSS version 24 software. Results: A total of 60 patients were included in the study. The mean ages in the CSF and CNF groups were 49.8±9.6 and 49.6±10.7 yrs, respectively. In the CSF group, 63.33% were female, compared to 43.33% in the CNF group. There were statistically significant differences in Em and aortic aortic Velocity Time Integral (VTI) among echocardiographic variables (p<0.05). However, PSW velocity did not significantly differ between the CNF and CSF groups (33.6±17.4 vs. 37.8±10.4, p=0.26), though it was slightly higher in slow flow patients. Conclusion: In this study, no significant difference was found in PSW velocity between patients with slow coronary flow and those with normal coronary flow, and it is not associated with arterial stiffness. Therefore, PSW velocity cannot be used as a predictor of arterial stiffness in CSF patients. Further research is recommended to validate or refute these findings.