Considerations in Pursuing Reaction Scope Generality

Abstract The term “generality” has recently been popularized in synthetic chemistry, owing largely to the increasing use of high‐throughput technology for producing vast quantities of data and the emergence of data science tools to plan and interpret these experiments. Despite this, the term has not been clearly defined, and there is no standardized approach toward developing a method with a diverse (general) scope. This minireview will examine different emerging strategies toward achieving generality using selected examples and aims to give the reader an overview of modern workflows that have been used to expedite this pursuit.

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Publication Details

Journal
Angewandte Chemie
Published
2025-09-09
DOI
https://doi.org/10.1002/ange.202511091
Citations
1
Primary Topic
Chemical Synthesis and Analysis
Type
article
Field-Weighted Citation Impact
0.81
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article

Considerations in Pursuing Reaction Scope Generality

Matthew S. Sigman, Samson B. Zacate, Juliana A. Dantas, Song Lin et al.
1 citations
Angewandte Chemie
Chemical Synthesis and Analysis
0.81
article

Considerations in Pursuing Reaction Scope Generality

Matthew S. Sigman, Samson B. Zacate, Juliana A. Dantas, Song Lin, Abigail G. Doyle
article en
1 citations

Abstract

Abstract The term “generality” has recently been popularized in synthetic chemistry, owing largely to the increasing use of high‐throughput technology for producing vast quantities of data and the emergence of data science tools to plan and interpret these experiments. Despite this, the term has not been clearly defined, and there is no standardized approach toward developing a method with a diverse (general) scope. This minireview will examine different emerging strategies toward achieving generality using selected examples and aims to give the reader an overview of modern workflows that have been used to expedite this pursuit.

Angewandte ChemieVol. 137(41)
University of California, Los Angeles (US), Cornell University (US), University of Utah (US)
Openalex Percentile: Top 24%
Chemical Synthesis and Analysis
0.81
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