Ovarian Germ Cell Tumor in Pregnancy: A Case Report

Background: Ovarian germ cell tumors (OGCTs) are a rare form of ovarian cancer, especially during pregnancy, and their diagnosis and management present unique challenges. These tumors account for a small percentage of all ovarian cancers, and their diagnosis is often complicated because of non-specific symptoms that overlap with normal pregnancy. Case Presentation: A 26-year-old pregnant woman, G1P0000, presented with an enlarging abdominal mass at 16 weeks of gestation. Ultrasound and CT tomography revealed a solid ovarian mass. The patient was diagnosed with a suspected malignant ovarian germ cell tumor and underwent unilateral salpingo-oophorectomy using frozen sections. Histopathological examination confirmed the tumor to be a mixed germ cell tumor, predominantly the yolk sac and dysgerminoma components. Conclusion: Early diagnosis and management of ovarian germ cell tumors during pregnancy are crucial for ensuring maternal and fetal well-being. Surgical intervention remains the primary treatment option, and fertility preservation of should be considered whenever possible. Post-operatively, the patient recovered well, and further chemotherapy with BEP was planned.

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Publication Details

Journal
European Journal of Medical and Health Sciences
Published
2025-09-09
DOI
https://doi.org/10.24018/ejmed.2025.7.5.2336
Primary Topic
Testicular diseases and treatments
Type
article
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article

Ovarian Germ Cell Tumor in Pregnancy: A Case Report

I Gde Sastra Winata, Vidya Saraswati Putri Duarsa
European Journal of Medical and Health Sciences
Testicular diseases and treatments
article

Ovarian Germ Cell Tumor in Pregnancy: A Case Report

I Gde Sastra Winata, Vidya Saraswati Putri Duarsa
article en

Abstract

Background: Ovarian germ cell tumors (OGCTs) are a rare form of ovarian cancer, especially during pregnancy, and their diagnosis and management present unique challenges. These tumors account for a small percentage of all ovarian cancers, and their diagnosis is often complicated because of non-specific symptoms that overlap with normal pregnancy. Case Presentation: A 26-year-old pregnant woman, G1P0000, presented with an enlarging abdominal mass at 16 weeks of gestation. Ultrasound and CT tomography revealed a solid ovarian mass. The patient was diagnosed with a suspected malignant ovarian germ cell tumor and underwent unilateral salpingo-oophorectomy using frozen sections. Histopathological examination confirmed the tumor to be a mixed germ cell tumor, predominantly the yolk sac and dysgerminoma components. Conclusion: Early diagnosis and management of ovarian germ cell tumors during pregnancy are crucial for ensuring maternal and fetal well-being. Surgical intervention remains the primary treatment option, and fertility preservation of should be considered whenever possible. Post-operatively, the patient recovered well, and further chemotherapy with BEP was planned.

European Journal of Medical and Health SciencesVol. 7(5)
Udayana University (ID), Pham Ngoc Thach Hospital (VN)
Openalex Percentile: Top 60%
Testicular diseases and treatments
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Ovarian Germ Cell Tumor in Pregnancy: A Case Report — I Gde Sastra Winata, Vidya Saraswati Putri Duarsa · European Journal of Medical and Health Sciences (2025) | TGRS Research Map | TGRS