Biological Information Transmission Modalities in the Normal Liver and in the Cirrhotic One. From Ligand Molecule to Oscillations, Waves and Fields

All physicians were used to approaching hepatic pathophysiology from the macroscopic level down to the level of molecular signaling and hepatocyte genomic response, where they stopped. This paper aims to approach the fractal reality called Life at an even deeper level. More specifically, this article is one of the few that aims to present the connection between biochemical and biophysical phenomena. Thus, we will try to present the spectacular events of intrahepatic signaling from the cellular to the quantum level. We believe it is extremely important for a physician to understand that normal and disease are actually particle-wave phenomena of informational exchange. We will first present how any signal from an extracellular ligand is transformed in the hepatocyte into calcium oscillations and waves, a phenomenon known for a long time. We will descend into the fractal and see how, under normal conditions, these calcium oscillations and waves are entangled with the oscillations and waves of ROSs generated in the mitochondria and how the entanglement disappears in liver pathology. We will see how the oscillations and intra- and intercellular waves of calcium and ROSs generate electromagnetic waves and how, at this level, the laws of quantum physics manifest themselves. Then how these electromagnetic (energetic) fields associate torsion (informational) fields, confirmed by the physics of recent years. Although torsion fields are classically considered pseudoscience because they lack sufficient experimental support, although torsion fields were classically considered pseudoscience because they lacked sufficient experimental support, this approach is now increasingly being disproven. Readers should remember that quantum mechanics was founded on a single empirical prouve: the double slit experiment. This is where Normal begins, this is where Disease begins.