Co-infection of HIV and intestinal parasites and their associated factors among HIV infected patients receiving antiretroviral Therapy (ART) in Abia Specialist Hospital and Diagnostic Center Amachara, Umuahia Abia State, Nigeria.

HIV-infected individuals are at increased risk of intestinal parasitic infections (IPIs), especially in resourcelimited settings.This study assessed the prevalence of IPIs and associated risk factors among HIV-positive adults on antiretroviral therapy (ART) in Southeastern Nigeria.A hospital-based cross-sectional study was conducted from June to September 2019 at Abia Specialist Hospital, Umuahia South LGA.A total of 200 HIVpositive adults on ART were systematically recruited, with 193 meeting inclusion criteria.Data on demographics, hygiene practices, and clinical parameters were collected via structured interviews.Stool and blood samples were analyzed for intestinal parasites, CD4 counts, and viral load.Data were analyzed using WINKS SDA, with significance set at p<0.05.The prevalence of intestinal parasitic infections was 14.5% (28/193).Entamoeba histolytica (4.1%) and Giardia lamblia (2.6%) were the most common parasites.Significant associations were observed between IPIs and diarrheal symptoms (p<0.001),CD4 count 200 cells/L (p=0.008), and viral load 1000 copies/mL (p=0.028).Employment status (p=0.024) and WHO clinical staging (p<0.001) also showed significant associations.However, sanitation and hygiene factors-including water source, toilet availability, barefoot walking, and exposure to stagnant water-were not significantly associated with infection (p>0.05).Intestinal parasitic infections remain a significant concern among HIVpositive individuals on ART, particularly those with low immunity and high viral load.Routine parasitological screening, especially for symptomatic and immunocompromised patients, is recommended to improve care outcomes in similar settings.

Publication Details

Journal
International Research Journal of Modernization in Engineering Technology and Science
Published
2025-09-15
DOI
https://doi.org/10.56726/irjmets82515
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
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article

Co-infection of HIV and intestinal parasites and their associated factors among HIV infected patients receiving antiretroviral Therapy (ART) in Abia Specialist Hospital and Diagnostic Center Amachara, Umuahia Abia State, Nigeria.

International Research Journal of Modernization in Engineering Technology and Science
HIV/AIDS Research and Interventions
article

Co-infection of HIV and intestinal parasites and their associated factors among HIV infected patients receiving antiretroviral Therapy (ART) in Abia Specialist Hospital and Diagnostic Center Amachara, Umuahia Abia State, Nigeria.

article en

Abstract

HIV-infected individuals are at increased risk of intestinal parasitic infections (IPIs), especially in resourcelimited settings.This study assessed the prevalence of IPIs and associated risk factors among HIV-positive adults on antiretroviral therapy (ART) in Southeastern Nigeria.A hospital-based cross-sectional study was conducted from June to September 2019 at Abia Specialist Hospital, Umuahia South LGA.A total of 200 HIVpositive adults on ART were systematically recruited, with 193 meeting inclusion criteria.Data on demographics, hygiene practices, and clinical parameters were collected via structured interviews.Stool and blood samples were analyzed for intestinal parasites, CD4 counts, and viral load.Data were analyzed using WINKS SDA, with significance set at p<0.05.The prevalence of intestinal parasitic infections was 14.5% (28/193).Entamoeba histolytica (4.1%) and Giardia lamblia (2.6%) were the most common parasites.Significant associations were observed between IPIs and diarrheal symptoms (p<0.001),CD4 count 200 cells/L (p=0.008), and viral load 1000 copies/mL (p=0.028).Employment status (p=0.024) and WHO clinical staging (p<0.001) also showed significant associations.However, sanitation and hygiene factors-including water source, toilet availability, barefoot walking, and exposure to stagnant water-were not significantly associated with infection (p>0.05).Intestinal parasitic infections remain a significant concern among HIVpositive individuals on ART, particularly those with low immunity and high viral load.Routine parasitological screening, especially for symptomatic and immunocompromised patients, is recommended to improve care outcomes in similar settings.

International Research Journal of Modernization in Engineering Technology and Science
Openalex Percentile: Top 70%
HIV/AIDS Research and Interventions
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Co-infection of HIV and intestinal parasites and their associated factors among HIV infected patients receiving antiretroviral Therapy (ART) in Abia Specialist Hospital and Diagnostic Center Amachara, Umuahia Abia State, Nigeria. · International Research Journal of Modernization in Engineering Technology and Science (2025) | TGRS Research Map | TGRS