Age-stratified gut microbial changes in diarrheal calves: insights from 16S rRNA sequencing across early development
NCD-associated dysbiosis progresses through distinct developmental phases, from resilient phylum-level shifts in neonates to complex network disruptions in mature microbiota. The identification of stage-specific biomarkers (e.g., day 21 <i>Kurthia</i>) opens new avenues for age-tailored probiotic therapies and early intervention strategies.
Authors
- Chunfu Li (ORCID: https://orcid.org/0000-0003-1858-2320)
- Fenqi Li
- Xinyu Feng (ORCID: https://orcid.org/0000-0002-4120-7759)
- Hao Yu (ORCID: https://orcid.org/0000-0002-9785-8489)
- Luyang Tang (ORCID: https://orcid.org/0000-0003-4074-1797)
- Yanli Zhang (ORCID: https://orcid.org/0000-0001-9661-3730)
- Wei Hu (ORCID: https://orcid.org/0000-0003-2985-5427)
- Jian Li (ORCID: https://orcid.org/0009-0001-9687-441X)
- Xinlei Fu
Institutions
- Shanghai Jiao Tong University (CN)
- Fudan University (CN)
- Inner Mongolia University (CN)
- Guangxi University of Chinese Medicine (CN)
- Huashan Hospital (CN)
- State Key Laboratory of Genetic Engineering
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-09-15
- DOI
- https://doi.org/10.3389/fmicb.2025.1633162
- Citations
- 1
- Primary Topic
- Gastrointestinal disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.01