Screening Multisystem Inflammatory Syndrome in Children: Accuracy of the American College of Rheumatology Screening Algorithm
The ACR MIS-C screening algorithm demonstrates high specificity, high accuracy, and good sensitivity in identifying children with MIS-C at disease onset. Despite being developed early in the pandemic with limited data available, the ACR algorithm effectively differentiates children with MIS-C from febrile controls.
Authors
- Trent Mizzi
- Paul Tsoukas (ORCID: https://orcid.org/0000-0002-1782-4458)
- Beth Gamulka
- Greta Mastrangelo (ORCID: https://orcid.org/0000-0002-3455-7304)
- Amy Xu (ORCID: https://orcid.org/0000-0001-9650-9458)
- Rae S. M. Yeung (ORCID: https://orcid.org/0000-0003-2361-725X)
- Arthur H. Cheng (ORCID: https://orcid.org/0000-0001-8214-1437)
Institutions
- University of Toronto (CA)
- Hospital for Sick Children (CA)
Publication Details
- Journal
- The Journal of Rheumatology
- Published
- 2025-09-15
- DOI
- https://doi.org/10.3899/jrheum.2025-0587
- Primary Topic
- Kawasaki Disease and Coronary Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00