Clinical and epidemiological features of juvenile-onset systemic sclerosis from a nationwide survey in Japan
This is the largest national survey of jSSc characteristics analyzed in detail by autoantibody and disease subtype. Japanese jSSc was characterized by a very high ATA positivity rate. However, the frequency of major organ involvement was similar to previous reports of jSSc in the West.
Authors
- Manabu Fujimoto (ORCID: https://orcid.org/0000-0002-3062-4872)
- Yoshihide Asano (ORCID: https://orcid.org/0000-0001-5560-9778)
- Utako Kaneko (ORCID: https://orcid.org/0009-0006-9162-336X)
- Ikuko Ueda‐Hayakawa (ORCID: https://orcid.org/0000-0002-1652-5691)
- Hiroki Takahashi (ORCID: https://orcid.org/0000-0003-0528-0446)
- Atsushi Kumanogoh (ORCID: https://orcid.org/0000-0003-4749-7117)
- Hideki Ishikawa (ORCID: https://orcid.org/0000-0001-5980-698X)
- Yohei Isomura (ORCID: https://orcid.org/0000-0003-1449-573X)
- Hidekata Yasuoka (ORCID: https://orcid.org/0000-0002-2405-6282)
- Naoko Okiyama (ORCID: https://orcid.org/0000-0002-5398-0773)
- Masaki Shimizu (ORCID: https://orcid.org/0000-0002-2019-6843)
- Masaru Hatano (ORCID: https://orcid.org/0000-0003-2135-3625)
- Katsunari Makino (ORCID: https://orcid.org/0000-0003-2603-9774)
- Sei‐ichiro Motegi (ORCID: https://orcid.org/0000-0001-8286-0669)
- Minoru Hasegawa (ORCID: https://orcid.org/0000-0003-3738-2682)
- Yasuhito Hamaguchi (ORCID: https://orcid.org/0000-0001-5305-7770)
- Yasuhiro Kanatani (ORCID: https://orcid.org/0000-0001-5790-4084)
- Toshiyuki Yamamoto (ORCID: https://orcid.org/0000-0002-8390-2573)
- Sumiaki Tanaka
- Takamitsu Makino (ORCID: https://orcid.org/0000-0003-3268-0365)
- Naoki Mugii (ORCID: https://orcid.org/0000-0003-3102-5676)
- Yoshihito Shima (ORCID: https://orcid.org/0000-0002-2523-2938)
- Masatoshi Jinnin (ORCID: https://orcid.org/0000-0001-9230-6207)
- Takashi Matsushita (ORCID: https://orcid.org/0000-0002-1617-086X)
- Ryusuke Ae (ORCID: https://orcid.org/0000-0003-2660-530X)
- Hisataka Maki
- Daisuke Goto (ORCID: https://orcid.org/0000-0001-6646-2003)
- Masataka Kuwana (ORCID: https://orcid.org/0000-0003-1249-985X)
- Yasushi Kawaguchi (ORCID: https://orcid.org/0000-0003-2025-1344)
- Yoshikazu Nakamura
- Ayumi Yoshizaki
- Takako Miyamae
Institutions
- Kanazawa University (JP)
- University of Fukui (JP)
- Tokyo Medical and Dental University (JP)
- Fukushima Medical University (JP)
- Tokai University (JP)
- Sapporo Medical University (JP)
- Fujita Health University (JP)
- Jichi Medical University (JP)
- Kanazawa Medical University (JP)
- Gunma University (JP)
- Wakayama Medical University (JP)
- Tohoku University (JP)
- Kyoto Prefectural University of Medicine (JP)
- Tokyo Women's Medical University Hospital (JP)
- Kanazawa University Hospital (JP)
- University of Tokyo Hospital (JP)
- Tokai University Hospital (JP)
- Tokyo Women's Medical University (JP)
- Ibaraki Prefectural Central Hospital (JP)
- Kitasato University Medical Center (JP)
- YKK (Japan) (JP)
- Kanazawa Hospital (JP)
- Aoyama Hospital Tokyo Women’s Medical University (JP)
- Jichi Medical University Saitama Medical Center (JP)
- Kitasato University (JP)
- Niigata University (JP)
- Nippon Medical School (JP)
- Kumamoto University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- The Journal of Rheumatology
- Published
- 2025-09-15
- DOI
- https://doi.org/10.3899/jrheum.2025-0175
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00