ANKK1 Taq1A Gene Variance and Executive Functions in Female Youth with Binge Eating Disorder: A Cross-sectional Study

No association was found between ANKK1 Taq1A gene variance and BED or EFs performance. The female youth with obesity and BED demonstrated worse cognitive flexibility and decision-making, along with greater depression severity. Worse cognitive flexibility and greater depression severity were found to increase the probability of BED. Thus, evaluating and addressing EF deficits in BED patients, along with managing co-morbid psychiatric conditions, is crucial for improving treatment outcomes.