Terahertz High-Sensitivity SPR Phase Biosensor Based on the Weyl Semimetals

Optical biosensors play a crucial role in the field of biological detection by converting biological signals into optical signals for detection. Among them, Surface Plasmon Resonance (SPR) optical biosensors have become a research hotspot in this field due to their significant advantage of high sensitivity. Weyl Semimetals (WSMs), as a type of three-dimensional topological material with unique electronic structures and other properties, exhibit potential applications in the field of SPR sensing. Against this background, we designed a terahertz (THz) high-sensitivity SPR phase biosensor with a KR structure based on WSMs. When applied in gas sensing scenarios, the phase detection sensitivity of this sensor can reach 22,402°/RIU, showing a significant improvement compared to traditional SPR biosensors. Moreover, we found that the Weyl node separation distance and twist angle of WSMs have obvious effects on sensitivity regulation. Additionally, we optimized the sensitivity and structural parameters of this structure using a neural network-based deep learning algorithm. We expect that this proposed scheme can provide a feasible reference for the field of biological sensing.

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Publication Details

Journal
Biosensors
Published
2025-09-15
DOI
https://doi.org/10.3390/bios15090606
Citations
1
Primary Topic
Plasmonic and Surface Plasmon Research
Type
article
Field-Weighted Citation Impact
0.67

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article

Terahertz High-Sensitivity SPR Phase Biosensor Based on the Weyl Semimetals

Mengjiao Ren, Mingwei Guo, Zhongrong Shen, Mingming Zhang et al.
1 citations
Biosensors
Plasmonic and Surface Plasmon Research
0.67
article

Terahertz High-Sensitivity SPR Phase Biosensor Based on the Weyl Semimetals

Mengjiao Ren, Mingwei Guo, Zhongrong Shen, Mingming Zhang, Yangli Xie, Leyong Jiang
article en
1 citations

Abstract

Optical biosensors play a crucial role in the field of biological detection by converting biological signals into optical signals for detection. Among them, Surface Plasmon Resonance (SPR) optical biosensors have become a research hotspot in this field due to their significant advantage of high sensitivity. Weyl Semimetals (WSMs), as a type of three-dimensional topological material with unique electronic structures and other properties, exhibit potential applications in the field of SPR sensing. Against this background, we designed a terahertz (THz) high-sensitivity SPR phase biosensor with a KR structure based on WSMs. When applied in gas sensing scenarios, the phase detection sensitivity of this sensor can reach 22,402°/RIU, showing a significant improvement compared to traditional SPR biosensors. Moreover, we found that the Weyl node separation distance and twist angle of WSMs have obvious effects on sensitivity regulation. Additionally, we optimized the sensitivity and structural parameters of this structure using a neural network-based deep learning algorithm. We expect that this proposed scheme can provide a feasible reference for the field of biological sensing.

BiosensorsVol. 15(9)
Hunan Normal University (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 27%
Plasmonic and Surface Plasmon Research
0.67
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Terahertz High-Sensitivity SPR Phase Biosensor Based on the Weyl Semimetals — Mengjiao Ren, Mingwei Guo, et al. · Biosensors (2025) | TGRS Research Map | TGRS