Zoonotic Hepatitis E Virus Infection: Where Are We and Where Should We Look?

Zoonotic hepatitis E virus (HEV) causes a worldwide problem.Generally transmitted via infected animals/eating contaminated food.Fully understanding the distinctive biology, transmission routes, and clinical consequences of zoonotic HEV strains is essential for developing efficacious prevention and control tactics.Current knowledge gives prominence to animals, with pigs in particular being recognized as reservoirs, and examines the clinical variances between zoonotic and strictly human HEV genotypes.This analysis further explores recent advances in diagnostics, immunization efforts, and protective measures while identifying gaps in our comprehension, requiring additional research to better address HEV as a public health menace.Furthermore, strategies aiming to reduce potential zoonotic transmission through improved hygiene standards and strict inspection of the food supply chain merit consideration.