Median Arcuate Ligament Syndrome as a Rare Cause of Ischemic Duodenal Ulcers: A Case Report

The median arcuate ligament syndrome is a rare cause of postprandial abdominal pain. Diagnosis is often delayed because of the heterogeneous presentation. This case report describes a patient with worsening epigastric pain and a new onset of gastrointestinal bleeding after a robot-assisted median arcuate ligament release. Diagnostic angiography showed a patent celiac artery without residual stenosis, whereas multiple ischemic and hemorrhagic duodenal ulcers were observed upon gastroscopy. After additional medical treatment with high-dose proton pump inhibitors, the patient became asymptomatic with complete healing of the ulcer. This finding is unusual, as duodenal ulcers are not typically suggestive of median arcuate ligament syndrome. Therefore, median arcuate ligament syndrome should be considered as a contributing factor in patients with therapy-resistant duodenal ulcers.

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Publication Details

Journal
Cureus
Published
2025-09-15
DOI
https://doi.org/10.7759/cureus.92370
Primary Topic
Abdominal vascular conditions and treatments
Type
article
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article

Median Arcuate Ligament Syndrome as a Rare Cause of Ischemic Duodenal Ulcers: A Case Report

Sandra Müller, R Sebrechts, Patrick Lauwers, Jeroen Hendriks et al.
Cureus
Abdominal vascular conditions and treatments
article

Median Arcuate Ligament Syndrome as a Rare Cause of Ischemic Duodenal Ulcers: A Case Report

Sandra Müller, R Sebrechts, Patrick Lauwers, Jeroen Hendriks, Lieselot Potums
article en

Abstract

The median arcuate ligament syndrome is a rare cause of postprandial abdominal pain. Diagnosis is often delayed because of the heterogeneous presentation. This case report describes a patient with worsening epigastric pain and a new onset of gastrointestinal bleeding after a robot-assisted median arcuate ligament release. Diagnostic angiography showed a patent celiac artery without residual stenosis, whereas multiple ischemic and hemorrhagic duodenal ulcers were observed upon gastroscopy. After additional medical treatment with high-dose proton pump inhibitors, the patient became asymptomatic with complete healing of the ulcer. This finding is unusual, as duodenal ulcers are not typically suggestive of median arcuate ligament syndrome. Therefore, median arcuate ligament syndrome should be considered as a contributing factor in patients with therapy-resistant duodenal ulcers.

CureusVol. 17(9)
Antwerp University Hospital (BE)
Openalex Percentile: Top 60%
Abdominal vascular conditions and treatments
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