Intraoperative Recognition and Anesthetic Management of Myxedema Coma During Emergent Intertrochanteric Femur Fracture Repair

Myxedema coma is a rare, life-threatening complication of severe, long-standing hypothyroidism, often precipitated by physiological stress such as infection, trauma, or surgery. Perioperative presentations of myxedema coma are especially uncommon. This case report describes a 71-year-old male with a history of poorly controlled hypothyroidism who underwent emergent surgical fixation of a traumatic left intertrochanteric femur fracture who developed intraoperative myxedema coma. Timely diagnosis and intervention-including intravenous thyroid hormone replacement, corticosteroids, hemodynamic support, and close anesthetic management were crucial to optimizing the patient's outcome. This report highlights the critical role of anesthetic management in myxedema coma cases, emphasizing the importance of endocrine and hemodynamic support. Furthermore, it promotes multidisciplinary coordination when managing endocrinological emergencies in high-risk surgical patients.

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Publication Details

Journal
Orthopedic Reviews
Published
2025-09-15
DOI
https://doi.org/10.52965/001c.143086
Primary Topic
Cardiac, Anesthesia and Surgical Outcomes
Type
article
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article

Intraoperative Recognition and Anesthetic Management of Myxedema Coma During Emergent Intertrochanteric Femur Fracture Repair

Anvinh Nguyen, Jamal Hasoon, Maria J Lopez, Arusa Macnojia
Orthopedic Reviews
Cardiac, Anesthesia and Surgical Outcomes
article

Intraoperative Recognition and Anesthetic Management of Myxedema Coma During Emergent Intertrochanteric Femur Fracture Repair

Anvinh Nguyen, Jamal Hasoon, Maria J Lopez, Arusa Macnojia
article en

Abstract

Myxedema coma is a rare, life-threatening complication of severe, long-standing hypothyroidism, often precipitated by physiological stress such as infection, trauma, or surgery. Perioperative presentations of myxedema coma are especially uncommon. This case report describes a 71-year-old male with a history of poorly controlled hypothyroidism who underwent emergent surgical fixation of a traumatic left intertrochanteric femur fracture who developed intraoperative myxedema coma. Timely diagnosis and intervention-including intravenous thyroid hormone replacement, corticosteroids, hemodynamic support, and close anesthetic management were crucial to optimizing the patient's outcome. This report highlights the critical role of anesthetic management in myxedema coma cases, emphasizing the importance of endocrine and hemodynamic support. Furthermore, it promotes multidisciplinary coordination when managing endocrinological emergencies in high-risk surgical patients.

Orthopedic ReviewsVol. 17
Baylor College of Medicine (US), The University of Texas Health Science Center at Houston (US)
Openalex Percentile: Top 62%
Cardiac, Anesthesia and Surgical Outcomes
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