Clinical and Molecular Profiles and Treatment Outcomes in Patients With Acute Promyelocytic Leukaemia: A Single-Centre Experience
Most patients with APL presented with fever and bleeding. The bcr1 transcript of PML-RARα was the most commonly observed. ATRA and ATO-based treatment was associated with high remission rates, manageable toxicity, and a low relapse rate.
Authors
- Purvish M. Parikh (ORCID: https://orcid.org/0000-0003-3813-8788)
- Omkar Kalidasrao Choudhari (ORCID: https://orcid.org/0000-0001-9993-090X)
- Hemant Malhotra (ORCID: https://orcid.org/0000-0001-5613-5375)
- Lalit Mohan Sharma (ORCID: https://orcid.org/0000-0002-3262-6708)
- Naveen Gupta (ORCID: https://orcid.org/0000-0002-2695-1985)
- Ajay Yadav (ORCID: https://orcid.org/0000-0001-8507-3767)
- Satyajeet Soni (ORCID: https://orcid.org/0000-0003-2564-2619)
- Priyanka Soni
- Disha SATYA (ORCID: https://orcid.org/0009-0001-7251-3441)
Institutions
- Gandhi Medical College & Hospital (IN)
Publication Details
- Journal
- Cureus
- Published
- 2025-09-15
- DOI
- https://doi.org/10.7759/cureus.92377
- Primary Topic
- Retinoids in leukemia and cellular processes
- Type
- article
- Field-Weighted Citation Impact
- 0.00