Survival Time Analysis of Multiple Myeloma Patients using Type 1 Censored Exponential Distribution Parameter Estimation

Multiple myeloma is a type of blood cancer that attacks plasma cells in the bone marrow and affects the immune system. This study analyzes the survival time of patients with multiple myeloma using Type 1 censored exponential distributed parameter estimation. The data, consisting of 47 patients (35 uncensored and 12 censored), were tested for exponential distribution fit using the Anderson-Darling test, yielding a p-value of 0.495, confirming the suitability of the exponential model. The maximum likelihood estimation method was applied, resulting in a parameter estimate (θ ̂) of approximately 54.028 days, representing the mean survival time. Hypothesis testing and confidence intervals were conducted, with the 95% confidence interval for θ_0 ranging between 32 and 53 days. The findings suggest that the exponential distribution effectively models the survival data, providing insights into patient survival trends and supporting clinical decision-making.

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Publication Details

Journal
JTAM (Jurnal Teori dan Aplikasi Matematika)
Published
2025-07-30
DOI
https://doi.org/10.31764/jtam.v9i3.32179
Primary Topic
Statistical Distribution Estimation and Applications
Type
article
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article

Survival Time Analysis of Multiple Myeloma Patients using Type 1 Censored Exponential Distribution Parameter Estimation

Idrus Syahzaqi, Ardi Kurniawan, Cahya Arsyika Wahyu Subekti, Inas Nilasari et al.
JTAM (Jurnal Teori dan Aplikasi Matematika)
Statistical Distribution Estimation and Applications
article

Survival Time Analysis of Multiple Myeloma Patients using Type 1 Censored Exponential Distribution Parameter Estimation

Idrus Syahzaqi, Ardi Kurniawan, Cahya Arsyika Wahyu Subekti, Inas Nilasari, Devi Mufidah Syarif
article en

Abstract

Multiple myeloma is a type of blood cancer that attacks plasma cells in the bone marrow and affects the immune system. This study analyzes the survival time of patients with multiple myeloma using Type 1 censored exponential distributed parameter estimation. The data, consisting of 47 patients (35 uncensored and 12 censored), were tested for exponential distribution fit using the Anderson-Darling test, yielding a p-value of 0.495, confirming the suitability of the exponential model. The maximum likelihood estimation method was applied, resulting in a parameter estimate (θ ̂) of approximately 54.028 days, representing the mean survival time. Hypothesis testing and confidence intervals were conducted, with the 95% confidence interval for θ_0 ranging between 32 and 53 days. The findings suggest that the exponential distribution effectively models the survival data, providing insights into patient survival trends and supporting clinical decision-making.

JTAM (Jurnal Teori dan Aplikasi Matematika)Vol. 9(3)
Openalex Percentile: Top 76%
Statistical Distribution Estimation and Applications
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