Predictors and outcomes of coronary ectasia presenting with acute coronary syndrome

Objective: This study aimed to evaluate the predictors and clinical outcomes of coronary artery ectasia (CAE) in patients presenting with acute coronary syndromes (ACS).Methods: Study included patients diagnosed with CAE who presented with ACS, and the control group, consisted of 280 randomly selected ACS patients without CAE.Percutaneous coronary intervention (PCI) techniques are detailed in the full manuscript.All patients were followed for one year, with half followed for up to two years.Results: Male patients prevail in both groups (93% and 71%, respectively).Medical management was higher in CAE vs control group (34.6% vs 15%), while PCI was performed less in CAE than in control group (56.5% vs.77.8%) and coronary bypass surgery was performed in 8.9% and 7% of cases in each group.Mortality was significantly higher in the CAE group (8.2%) compared to the control group (2.8%) (p<0.05).Independent predictors of mortality included male sex (p=0.010),history of previous ACS (p=0.021), and presentation with ST-elevation myocardial infarction (p=0.018).Thrombus aspiration was performed in 26% of cases with CAE and balloon angioplasty was used in 111 patients (94%) with CAE, but both not have a significant impact on outcomes.Conclusions: These findings underscore the elevated mortality risk associated with CAE in ACS patients and highlight the need for further research to define optimal management strategies.