HLA-G 14 bp polymorphism: Implications and its associated risk to malaria severity among iron-fortified Ghanaian infants and young children

The study results indicated that iron-fortified individuals carrying the HLA-G 14 bp insertion/deletion polymorphism have an elevated risk of developing severe malaria, which in turn predisposes them to anaemia.

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Publication Details

Journal
PLoS ONE
Published
2025-09-15
DOI
https://doi.org/10.1371/journal.pone.0322524
Citations
1
Primary Topic
Reproductive System and Pregnancy
Type
article
Field-Weighted Citation Impact
0.80
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article

HLA-G 14 bp polymorphism: Implications and its associated risk to malaria severity among iron-fortified Ghanaian infants and young children

Christian Sewor, Samuel Kofi Tchum, Gideon Kwesi Nakotey, Samuel Asamoah Sakyi et al.
1 citations
PLoS ONE
Reproductive System and Pregnancy
0.80
article

HLA-G 14 bp polymorphism: Implications and its associated risk to malaria severity among iron-fortified Ghanaian infants and young children

Christian Sewor, Samuel Kofi Tchum, Gideon Kwesi Nakotey, Samuel Asamoah Sakyi, Nana Afriyie Duah, Agyemang Danquah, Benjamin Amoani, David Courtin, Alisé Lagrave
article en
1 citations

Abstract

The study results indicated that iron-fortified individuals carrying the HLA-G 14 bp insertion/deletion polymorphism have an elevated risk of developing severe malaria, which in turn predisposes them to anaemia.

PLoS ONEVol. 20(9)
University of Cape Coast (GH), Université Paris Cité (FR), Kwame Nkrumah University of Science and Technology (GH), Central University (GH), Mère et enfant en milieu tropical : pathogènes, système de santé et transition épidémiologique (FR), Kintampo Health Research Centre (GH), Ghana Health Service (GH), Institut de Recherche pour le Développement (FR)
Openalex Percentile: Top 24%
Reproductive System and Pregnancy
0.80
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HLA-G 14 bp polymorphism: Implications and its associated risk to malaria severity among iron-fortified Ghanaian infants and young children — Christian Sewor, Samuel Kofi Tchum, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS