Estimation of discrete mixed Poisson-Erlang distribution with applications to medical data

This paper discusses the estimation of the discrete mixed Poisson-Erlang distribution (DMPED). Compared to many traditional discrete distributions, DMPED offers several surprising benefits, especially when examining count data with high variation and that are positively skewed. We have explored several statistical characteristics of the assumed distribution, such as moments, the moment-generating function, the failure rate function, the monotonicity of the probability mass function, and a couple of descriptive measures (central tendency and dispersion). We have used the maximum likelihood estimation technique to estimate the parameters of the DMPED. We conducted a simulation study to validate the proposed estimators. Finally, four applications related to cancer diseases have been discussed, where DMPED (especially DMPEIID) fits the number of doses required for treatment, remission times, and therapy type comparisons.

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Publication Details

Journal
PLoS ONE
Published
2025-09-15
DOI
https://doi.org/10.1371/journal.pone.0331472
Primary Topic
Statistical Distribution Estimation and Applications
Type
article
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article

Estimation of discrete mixed Poisson-Erlang distribution with applications to medical data

Sadiah M. A. Aljeddani, Mahmoud Hamed Abu-Moussa, Mohamed Ahmed Mosilhy
PLoS ONE
Statistical Distribution Estimation and Applications
article

Estimation of discrete mixed Poisson-Erlang distribution with applications to medical data

Sadiah M. A. Aljeddani, Mahmoud Hamed Abu-Moussa, Mohamed Ahmed Mosilhy
article en

Abstract

This paper discusses the estimation of the discrete mixed Poisson-Erlang distribution (DMPED). Compared to many traditional discrete distributions, DMPED offers several surprising benefits, especially when examining count data with high variation and that are positively skewed. We have explored several statistical characteristics of the assumed distribution, such as moments, the moment-generating function, the failure rate function, the monotonicity of the probability mass function, and a couple of descriptive measures (central tendency and dispersion). We have used the maximum likelihood estimation technique to estimate the parameters of the DMPED. We conducted a simulation study to validate the proposed estimators. Finally, four applications related to cancer diseases have been discussed, where DMPED (especially DMPEIID) fits the number of doses required for treatment, remission times, and therapy type comparisons.

PLoS ONEVol. 20(9)
Cairo University (EG), Umm al-Qura University (SA), Sohar University (OM)
Openalex Percentile: Top 76%
Statistical Distribution Estimation and Applications
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