<i>Lactobacillus johnsonii</i> Synthesizes Chenodeoxycholic Acid to Reduce Susceptibility to High-Fat Diet–Induced Colorectal Cancer
Investigation of bacteria-host interactions that alter cancer susceptibility uncovers suppression of high-fat diet-induced colorectal cancer by Lactobacillus johnsonii, offering a translational approach to improve cancer prevention. See related commentary by Dalal and Shah, p. 4579.
Authors
- Peng Lai (ORCID: https://orcid.org/0009-0004-1110-4275)
- Danling Liu (ORCID: https://orcid.org/0009-0007-9313-6378)
- Junli Gong (ORCID: https://orcid.org/0000-0002-4732-055X)
- Xiaosheng He (ORCID: https://orcid.org/0000-0002-8346-4972)
- Jiancong Hu (ORCID: https://orcid.org/0000-0003-1116-4177)
- Zhanhao Luo (ORCID: https://orcid.org/0009-0001-7743-9850)
- Shengmei Yin (ORCID: https://orcid.org/0009-0001-6218-6977)
- Chen Liu (ORCID: https://orcid.org/0009-0008-2829-9135)
- Zhen He (ORCID: https://orcid.org/0000-0001-8735-6672)
- Shuang Guo (ORCID: https://orcid.org/0009-0001-6465-6119)
- Jing Yu (ORCID: https://orcid.org/0009-0005-8220-0931)
- Dayi Liang (ORCID: https://orcid.org/0009-0000-2679-9963)
- Ping Lan (ORCID: https://orcid.org/0000-0002-5225-5027)
- Guangyuan Chen (ORCID: https://orcid.org/0009-0004-2732-7561)
- Mengze Xing (ORCID: https://orcid.org/0009-0005-9854-304X)
Institutions
- Sun Yat-sen University (CN)
- Wuhan Dongxihu District People Hospital (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
- Key Laboratory of Guangdong Province (CN)
- State Key Laboratory of Oncology in South China
Publication Details
- Journal
- Cancer Research
- Published
- 2025-09-15
- DOI
- https://doi.org/10.1158/0008-5472.can-25-0879
- Citations
- 1
- Primary Topic
- Cancer Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.23