Progressive Encephalomyelitis With Rigidity and Myoclonus With Glycine Receptor Antibodies
GlyR antibody-mediated PERM is a rapidly progressive and severe disease that predominantly affects men and frequently presents with brainstem involvement. Its distinct demographic and clinical features suggest that it should be considered separately from SPSDs, which typically follows a chronic course and is more commonly associated with glutamic acid decarboxylase antibodies.
Authors
- Kazuyuki Noda (ORCID: https://orcid.org/0000-0002-5847-0596)
- Motoi Takenaka (ORCID: https://orcid.org/0000-0002-7045-2518)
- SJ Leandro Sequeiros
- Juntaro Kaneko
- Jordi González-Menacho
- Francesc Graus (ORCID: https://orcid.org/0000-0002-8924-8322)
- M. Zurdo
- L. Aguilar (ORCID: https://orcid.org/0000-0002-1553-2224)
- Takahiro Iizuka (ORCID: https://orcid.org/0000-0002-7234-0720)
- Mar Guasp (ORCID: https://orcid.org/0000-0002-0110-5213)
- Josep Dalmau (ORCID: https://orcid.org/0000-0001-5856-2813)
- Jordi Bruna (ORCID: https://orcid.org/0000-0001-6895-5047)
- Albert Saiz (ORCID: https://orcid.org/0000-0002-5793-8791)
- A Molina
- Mateus Mistieri Simabukuro (ORCID: https://orcid.org/0000-0001-9243-3337)
- Míriam Almendrote (ORCID: https://orcid.org/0000-0003-0212-275X)
- Francisco Antonio Martínez-García
- Marina Ruiz-Vives
Institutions
- Universitat Autònoma de Barcelona (ES)
- Hospital de Sant Pau (ES)
- Bellvitge University Hospital (ES)
- University Hospital Complex Of Vigo (ES)
- Institut d'Investigació Biomédica de Bellvitge (ES)
- Institut de Recerca Biomèdica Catalunya Sud (ES)
- Cicatelli Associates (US)
- Hospital Universitario Puerta de Hierro Majadahonda (ES)
- Hospital Clínic de Barcelona (ES)
- Juntendo University Shizuoka Hospital (JP)
- Chugoku Rosai Hospital (JP)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
- Hospital Universitario Virgen de la Arrixaca (ES)
- Hospital Universitari Germans Trias i Pujol (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Hospital Virgen del Puerto (ES)
- Kitasato University (JP)
- University of Pennsylvania (US)
Publication Details
- Journal
- Neurology Neuroimmunology & Neuroinflammation
- Published
- 2025-09-15
- DOI
- https://doi.org/10.1212/nxi.0000000000200473
- Citations
- 2
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.78