A case report of a multivessel coronary vasospasm that responded to IV diazepam

This case demonstrates multivessel CAVS refractory to standard vasodilators but responsive to IV diazepam, as evidenced by angiographic resolution. The temporal association with a panic attack suggests a link to psychological stress, aligning with literature on stress-related cardiovascular events. Limitations include the single-case design, lack of provocation testing, and inability to definitively establish causality between anxiety and vasospasm, necessitating larger studies to confirm IV diazepam's efficacy. Multivessel CAVS may respond to IV diazepam when standard treatments fail, particularly in cases associated with psychological stress. This case underscores the need for further research to validate the therapeutic potential of IV benzodiazepines in managing CAVS and to explore the interplay between psychological stress and cardiovascular events.

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Publication Details

Journal
Medicine
Published
2025-09-12
DOI
https://doi.org/10.1097/md.0000000000044267
Primary Topic
Cardiac Imaging and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00
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article

A case report of a multivessel coronary vasospasm that responded to IV diazepam

Farah Haneyah, Ghassan Bayat, Ahmad Alsaadi, M. Mohd Zain et al.
Medicine
Cardiac Imaging and Diagnostics
article

A case report of a multivessel coronary vasospasm that responded to IV diazepam

Farah Haneyah, Ghassan Bayat, Ahmad Alsaadi, M. Mohd Zain, Fares Abboud, Amal Jama
article en

Abstract

This case demonstrates multivessel CAVS refractory to standard vasodilators but responsive to IV diazepam, as evidenced by angiographic resolution. The temporal association with a panic attack suggests a link to psychological stress, aligning with literature on stress-related cardiovascular events. Limitations include the single-case design, lack of provocation testing, and inability to definitively establish causality between anxiety and vasospasm, necessitating larger studies to confirm IV diazepam's efficacy. Multivessel CAVS may respond to IV diazepam when standard treatments fail, particularly in cases associated with psychological stress. This case underscores the need for further research to validate the therapeutic potential of IV benzodiazepines in managing CAVS and to explore the interplay between psychological stress and cardiovascular events.

MedicineVol. 104(37)
Al-Balqa Applied University (JO), Al Assad University Hospital (SY), University Hospitals Plymouth NHS Trust (GB), Damascus University (SY), Gazi University (TR)
Openalex Percentile: Top 66%
Cardiac Imaging and Diagnostics
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A case report of a multivessel coronary vasospasm that responded to IV diazepam — Farah Haneyah, Ghassan Bayat, et al. · Medicine (2025) | TGRS Research Map | TGRS