A case report of a multivessel coronary vasospasm that responded to IV diazepam
This case demonstrates multivessel CAVS refractory to standard vasodilators but responsive to IV diazepam, as evidenced by angiographic resolution. The temporal association with a panic attack suggests a link to psychological stress, aligning with literature on stress-related cardiovascular events. Limitations include the single-case design, lack of provocation testing, and inability to definitively establish causality between anxiety and vasospasm, necessitating larger studies to confirm IV diazepam's efficacy. Multivessel CAVS may respond to IV diazepam when standard treatments fail, particularly in cases associated with psychological stress. This case underscores the need for further research to validate the therapeutic potential of IV benzodiazepines in managing CAVS and to explore the interplay between psychological stress and cardiovascular events.
Authors
- Farah Haneyah
- Ghassan Bayat
- Ahmad Alsaadi
- M. Mohd Zain
- Fares Abboud (ORCID: https://orcid.org/0009-0003-9647-9588)
- Amal Jama
Institutions
- Al-Balqa Applied University (JO)
- Al Assad University Hospital (SY)
- University Hospitals Plymouth NHS Trust (GB)
- Damascus University (SY)
- Gazi University (TR)
Publication Details
- Journal
- Medicine
- Published
- 2025-09-12
- DOI
- https://doi.org/10.1097/md.0000000000044267
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00