Successful Management of Cesarean Scar Ectopic Pregnancy Using Local Methotrexate Injection and Balloon Catheter Compression: A Case Report

Cesarean scar ectopic pregnancy (CSEP) is a form of non-tubal ectopic pregnancy. The diagnosis is made based on a combination of elevated beta human chorionic gonadotropin (β-hCG) levels and transvaginal ultrasound findings. In this case, a 32-year-old woman at 6.5 weeks gestation presented with abdominal cramping and vaginal bleeding. Transvaginal ultrasound confirmed a gestational sac implanted in the cesarean scar. After multidisciplinary consultation between obstetrics/gynecology and interventional radiology, the patient underwent ultrasound-guided intra-gestational methotrexate injection followed by balloon catheter compression. The results of the procedure included a rapid decline in β-hCG levels and resolution of the ectopic pregnancy. This case demonstrates the effectiveness of combining medical and mechanical interventions in early-stage CSEP and reinforces the importance of early diagnosis and coordinated care. Further research is needed to develop standardized treatment protocols for this rare condition.

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Publication Details

Journal
Cureus
Published
2025-09-15
DOI
https://doi.org/10.7759/cureus.92400
Primary Topic
Ectopic Pregnancy Diagnosis and Management
Type
article
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0.00
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article

Successful Management of Cesarean Scar Ectopic Pregnancy Using Local Methotrexate Injection and Balloon Catheter Compression: A Case Report

Nayana George, Reham R. Haroun, Madhav Barot
Cureus
Ectopic Pregnancy Diagnosis and Management
article

Successful Management of Cesarean Scar Ectopic Pregnancy Using Local Methotrexate Injection and Balloon Catheter Compression: A Case Report

Nayana George, Reham R. Haroun, Madhav Barot
article en

Abstract

Cesarean scar ectopic pregnancy (CSEP) is a form of non-tubal ectopic pregnancy. The diagnosis is made based on a combination of elevated beta human chorionic gonadotropin (β-hCG) levels and transvaginal ultrasound findings. In this case, a 32-year-old woman at 6.5 weeks gestation presented with abdominal cramping and vaginal bleeding. Transvaginal ultrasound confirmed a gestational sac implanted in the cesarean scar. After multidisciplinary consultation between obstetrics/gynecology and interventional radiology, the patient underwent ultrasound-guided intra-gestational methotrexate injection followed by balloon catheter compression. The results of the procedure included a rapid decline in β-hCG levels and resolution of the ectopic pregnancy. This case demonstrates the effectiveness of combining medical and mechanical interventions in early-stage CSEP and reinforces the importance of early diagnosis and coordinated care. Further research is needed to develop standardized treatment protocols for this rare condition.

CureusVol. 17(9)
Michigan State University (US)
Openalex Percentile: Top 67%
Ectopic Pregnancy Diagnosis and Management
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