Effects of Clinacanthus nutans Extracts on Cell Proliferation and Apoptosis in Triple-Negative Breast Cancer: Mechanistic Insights
CnE inhibits TNBC cell proliferation, suppresses tumor growth, The mechanism likely involves multiple biological processes and pathways, Key pathways included apoptosis, ferroptosis, and necroptosis signaling.
Authors
- Huifang He
- Yongkang Zhu
- Shaoqian Yin (ORCID: https://orcid.org/0009-0007-2174-6417)
- Naizhen Wang
- Zhen Li (ORCID: https://orcid.org/0000-0003-0519-2905)
- Yu Liu (ORCID: https://orcid.org/0000-0001-8723-1896)
- Yonggang Zhang (ORCID: https://orcid.org/0000-0003-4285-1236)
- Peng Wang (ORCID: https://orcid.org/0000-0001-8350-691X)
- Hai Li (ORCID: https://orcid.org/0000-0002-0485-4981)
- Chaoqun Wang (ORCID: https://orcid.org/0000-0002-2210-4340)
- Qiang Gao (ORCID: https://orcid.org/0000-0002-0742-4792)
- Renjun Feng (ORCID: https://orcid.org/0000-0003-1101-1293)
- Qingjie Hu
- Jinhua Long (ORCID: https://orcid.org/0000-0003-0325-4340)
- Jiafang Xu
- Shunxiong Tang
Institutions
- Nanjing University of Chinese Medicine (CN)
- People’s Hospital of Rizhao (CN)
- Hainan General Hospital (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- Breast Cancer Targets and Therapy
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/bctt.s528242
- Primary Topic
- Medicinal Plant Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00