Integrative proteomic characterization of human lung adenocarcinoma with KRAS G12 mutations reveals molecular pathogenesis
This comprehensive proteogenomic study provides insights into the molecular features of LUAD harboring KRAS G12 mutations, which may inform patient stratification and potential therapeutic approaches, pending further clinical validation.
Authors
- Xiaoyi Yuan (ORCID: https://orcid.org/0000-0002-2898-6495)
- Meifang Zhang (ORCID: https://orcid.org/0000-0001-6534-2480)
- Liling Hu (ORCID: https://orcid.org/0009-0003-0217-4290)
- Nengqiao Wen (ORCID: https://orcid.org/0000-0002-8387-4613)
- Xinyu Shi (ORCID: https://orcid.org/0000-0002-1220-4882)
- Fang Wang (ORCID: https://orcid.org/0009-0009-4639-4985)
- Ying Xue (ORCID: https://orcid.org/0000-0002-3053-5837)
- Qing‐Yu He (ORCID: https://orcid.org/0000-0003-0503-9492)
- Chris Zhiyi Zhang (ORCID: https://orcid.org/0000-0002-1944-8281)
- Xiaohui Tan
- Hong Yang (ORCID: https://orcid.org/0000-0002-8806-1240)
- Yi‐Ning Huang
- Jiangli Lu (ORCID: https://orcid.org/0000-0003-3099-3149)
- Huike Zou
Institutions
- Sun Yat-sen University (CN)
- Jinan University (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1016/j.jare.2025.09.014
- Citations
- 3
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 2.42