Association of Systemic Inflammatory Biomarkers (NLR, MLR, PLR, SII, SIRI) with Preeclampsia-Related Kidney Injury: A Retrospective Observational Study
MLR and SIRI are positively associated with PE-AKI risk, particularly in early-onset and complicated cases. This first comprehensive assessment of five biomarkers supports clinical utility. Prospective validation is required, with focus on monocyte-mediated inflammatory mechanisms.
Authors
- Chen De (ORCID: https://orcid.org/0009-0005-0358-3648)
- Xiaohui Liu (ORCID: https://orcid.org/0000-0001-7391-5058)
- Jian Liu (ORCID: https://orcid.org/0000-0001-8552-8805)
- Yan Dong (ORCID: https://orcid.org/0000-0002-5630-2724)
- Lina Gao (ORCID: https://orcid.org/0000-0003-0513-3059)
- Hong Guo (ORCID: https://orcid.org/0000-0001-6843-4997)
Institutions
- Lanzhou University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/jir.s542136
- Citations
- 1
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 2.06