An EDA complex-driven multicomponent reaction of Br–R <sub>f</sub> with alkenes <i>via</i> radical-polar crossover
We herein describe a general photo-induced EDA-enabled multicomponent reaction between alkenes, nitrogen heterocycles and Br-R<sub>f</sub>, offering a mild, operationally simple, and broadly applicable alternative to traditional post modification of nitrogen heterocycles. This reaction involved a cascade XAT/radical addition/radical polar crossover/radical addition to nitrogen heterocycles/HAT process.
Authors
- Wenchao Yang (ORCID: https://orcid.org/0000-0001-7729-7365)
- Shupeng Zhang (ORCID: https://orcid.org/0000-0001-6478-1537)
- Zhen Chen (ORCID: https://orcid.org/0009-0004-4532-4129)
- SM Lu
- Jin-Xin Lan
- Yicheng Zhang
Institutions
- Huaibei Normal University (CN)
- Yangzhou University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc03971a
- Citations
- 7
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 6.55