Prevalence of drug-drug interactions in children with cardiac disorders receiving off-label drugs in a single centre in Pakistan: a cross-sectional study

A high prevalence of CSDDIs and OL prescriptions was observed. OL drug presence was also observed to be a significant predictor associated with an increased risk of CSDDIs. Thus, to improve paediatric pharmacotherapy, suitable medical interventions are required to decrease OL drug use and CSDDIs.

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Publication Details

Journal
BMJ Paediatrics Open
Published
2025-09-01
DOI
https://doi.org/10.1136/bmjpo-2024-003293
Primary Topic
Pharmaceutical studies and practices
Type
article
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article

Prevalence of drug-drug interactions in children with cardiac disorders receiving off-label drugs in a single centre in Pakistan: a cross-sectional study

Kashif Barkat, Muhammad Fakhruddin Aamir, Shehla Akbar, Adeel Aslam et al.
BMJ Paediatrics Open
Pharmaceutical studies and practices
article

Prevalence of drug-drug interactions in children with cardiac disorders receiving off-label drugs in a single centre in Pakistan: a cross-sectional study

Kashif Barkat, Muhammad Fakhruddin Aamir, Shehla Akbar, Adeel Aslam, Naila Shahbaz, Anam Fatima, Samia Afaq
article en

Abstract

A high prevalence of CSDDIs and OL prescriptions was observed. OL drug presence was also observed to be a significant predictor associated with an increased risk of CSDDIs. Thus, to improve paediatric pharmacotherapy, suitable medical interventions are required to decrease OL drug use and CSDDIs.

BMJ Paediatrics OpenVol. 9(1)
University of Lahore (PK), University of the Punjab (PK), Sarhad University of Science and Information Technology (PK), Khyber Medical University (PK), Mahsa University (MY)
Openalex Percentile: Top 66%
Pharmaceutical studies and practices
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