A visible-light-mediated decarboxylative umpolung strategy to access carbamoyl/acyl fluorides in a buffer medium: expedient access to unsymmetrical ureas/amides and lysine-selective bioconjugation

A visible light mediated green process for the synthesis of carbamoyl/acyl fluorides followed by urea/amide formation for the modification of drugs and lysine-selective bioconjugation are demonstrated in a physiological buffer medium.

Authors

Subhodeep Das
Ranjan Jana (ORCID: https://orcid.org/0000-0002-5473-0258)
Abdur Rahaman (ORCID: https://orcid.org/0000-0002-8440-9633)
Sourav Mandal (ORCID: https://orcid.org/0000-0001-7859-9648)
Supriyo Das

Institutions

Indian Institute of Chemical Biology (IN)
Academy of Scientific and Innovative Research (IN)

Publication Details

Journal: Green Chemistry
Published: 2025-01-01
DOI: https://doi.org/10.1039/d5gc04556h
Primary Topic: Fluorine in Organic Chemistry
Type: article
Field-Weighted Citation Impact: 0.00

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article

A visible-light-mediated decarboxylative umpolung strategy to access carbamoyl/acyl fluorides in a buffer medium: expedient access to unsymmetrical ureas/amides and lysine-selective bioconjugation

Subhodeep Das, Ranjan Jana, Abdur Rahaman, Sourav Mandal et al.

Jan 1, 2025

Green Chemistry

Fluorine in Organic Chemistry

article

A visible-light-mediated decarboxylative umpolung strategy to access carbamoyl/acyl fluorides in a buffer medium: expedient access to unsymmetrical ureas/amides and lysine-selective bioconjugation

Subhodeep Das, Ranjan Jana, Abdur Rahaman, Sourav Mandal, Supriyo Das

January 1, 2025article en

Abstract

Green ChemistryVol. 27(42)

Indian Institute of Chemical Biology (IN), Academy of Scientific and Innovative Research (IN)

Openalex Percentile: Top 81%

Fluorine in Organic Chemistry

DOI Source OpenAlex

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A visible-light-mediated decarboxylative umpolung strategy to access carbamoyl/acyl fluorides in a buffer medium: expedient access to unsymmetrical ureas/amides and lysine-selective bioconjugation — Subhodeep Das, Ranjan Jana, et al. · Green Chemistry (2025) | TGRS Research Map | TGRS