Genetic variability of <i>HIF1A</i> and response to treatment with cisplatin in combination with pemetrexed or gemcitabine in patients with malignant mesothelioma
Among the investigated <i>HIF1A</i> SNPs, only rs11549465 has showed association with a worse response to chemotherapy after the adjustment for clinical parameters. The findings of this study have improved our understanding of the role of <i>HIF1A</i> polymorphisms in MM and may offer valuable insights into their impact on other cancers as well.
Authors
- Katja Goričar (ORCID: https://orcid.org/0000-0001-5673-4458)
- Vita Dolžan (ORCID: https://orcid.org/0000-0001-6707-6649)
- Marek Šetina
- Eva Setina
- Viljem Kovač (ORCID: https://orcid.org/0000-0003-0379-9041)
- Ziga Doljak
Institutions
- University of Ljubljana (SI)
- Institute of Oncology Ljubljana (SI)
Publication Details
- Journal
- Radiology and Oncology
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2478/raon-2025-0049
- Citations
- 1
- Primary Topic
- Occupational and environmental lung diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.52