Long Non-Coding RNA HOXA10-AS Promotes the Migration and Invasion of Glioblastoma Cells by Serving as a Competing Endogenous RNA for miR-99a-3p to Upregulate ITGB5 Expression
These results indicate that HOXA10-AS promotes tumorigenic behavior in glioblastoma cells by regulating the EMT-like process and functioning as an miR-99a-3p sponge to modulate ITGB5 levels, providing insights into glioblastoma development and potential therapeutic targets.
Authors
- Yongqiang Wang (ORCID: https://orcid.org/0000-0002-8149-1002)
- Yingjie Wang (ORCID: https://orcid.org/0000-0003-3938-8965)
- Qi Li (ORCID: https://orcid.org/0000-0002-8741-2205)
- Can Wang (ORCID: https://orcid.org/0000-0001-5332-6248)
- Cheng-Ya Dong
- Wanlin Dong
- Zirui Li (ORCID: https://orcid.org/0000-0002-6679-8006)
Institutions
- Capital Medical University (CN)
- Beijing Tian Tan Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
Publication Details
- Journal
- Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
- Published
- 2025-01-01
- DOI
- https://doi.org/10.32604/or.2025.068313
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00