The effect of decitabine on human induced pluripotent stem cells (hiPSCs) derived CD34+ cells expansion and the megakaryocytes generation and maturation
These results suggested that the effect of decitabine on CD34<sup>+</sup> cells from hiPSCs was very different from CB, PB and BM CD34<sup>+</sup> cells and the epigenetic changes may play an important role in the CD34<sup>+</sup> expansion and megakaryocytes maturation. It may provide a potential mechanism of studying hiPSCs derived HSCs and megakaryocytes maturation in the future.
Authors
- Yanfeng Liu (ORCID: https://orcid.org/0000-0003-2633-4765)
Institutions
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- American Journal of Stem Cells
- Published
- 2025-01-01
- DOI
- https://doi.org/10.62347/irbe1598
- Citations
- 1
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Shandong University
- Qilu Hospital of Shandong University
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province