Dual-stimuli responsive 4-arm PEG-SS-SN38 nanoparticles: ultrasound-controlled size switching and GSH-triggered release for enhanced pancreatic cancer penetration
Pancreatic ductal adenocarcinoma (PDAC) remains a lethal malignancy due to late-stage diagnosis and dense fibrotic stroma that impedes the penetration of drugs.
Authors
- Hongmian Jiang
- Junyu Wei (ORCID: https://orcid.org/0000-0002-0688-6370)
- Lifeng Luo (ORCID: https://orcid.org/0000-0003-2351-6045)
- Jinzhuai Li
- Chenxi Cui
- Zhi-Jie Liang (ORCID: https://orcid.org/0000-0002-0379-733X)
- Huali Huang
- Kun Zhao (ORCID: https://orcid.org/0000-0001-9871-4957)
Institutions
- Guangxi Medical University (CN)
- Shenzhen University (CN)
- Guangxi Normal University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
Publication Details
- Journal
- New Journal of Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5nj02274f
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00