Endothelial Activation and Stress Index as a Novel Prognostic Marker in Intrahepatic Cholestasis of Pregnancy: A Case–Control Study

This study demonstrates that the EASIX score may serve as an important prognostic tool in predicting disease severity and neonatal outcomes in ICP. Given the limited availability of bile acid measurements in some clinics, the EASIX score provides a practical and accessible alternative for clinical use. This study evaluates the prognostic value of the endothelial activation and stress index (EASIX) in intrahepatic cholestasis of pregnancy, highlighting its potential to predict disease severity and neonatal outcomes, offering a practical tool for clinical use.

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Publication Details

Journal
American Journal of Reproductive Immunology
Published
2025-09-01
DOI
https://doi.org/10.1111/aji.70167
Primary Topic
Drug Transport and Resistance Mechanisms
Type
article
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article

Endothelial Activation and Stress Index as a Novel Prognostic Marker in Intrahepatic Cholestasis of Pregnancy: A Case–Control Study

Merve Ayas Özkan, Ali Turhan Çağlar, Dilara Duygulu Bulan, Ruken Dayanan et al.
American Journal of Reproductive Immunology
Drug Transport and Resistance Mechanisms
article

Endothelial Activation and Stress Index as a Novel Prognostic Marker in Intrahepatic Cholestasis of Pregnancy: A Case–Control Study

Merve Ayas Özkan, Ali Turhan Çağlar, Dilara Duygulu Bulan, Ruken Dayanan, Zeynep Şeyhanlı, Gülşan Karabay
article en

Abstract

This study demonstrates that the EASIX score may serve as an important prognostic tool in predicting disease severity and neonatal outcomes in ICP. Given the limited availability of bile acid measurements in some clinics, the EASIX score provides a practical and accessible alternative for clinical use. This study evaluates the prognostic value of the endothelial activation and stress index (EASIX) in intrahepatic cholestasis of pregnancy, highlighting its potential to predict disease severity and neonatal outcomes, offering a practical tool for clinical use.

American Journal of Reproductive ImmunologyVol. 94(3)
Memorial Ankara Hospital (TR)
Openalex Percentile: Top 66%
Drug Transport and Resistance Mechanisms
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Endothelial Activation and Stress Index as a Novel Prognostic Marker in Intrahepatic Cholestasis of Pregnancy: A Case–Control Study — Merve Ayas Özkan, Ali Turhan Çağlar, et al. · American Journal of Reproductive Immunology (2025) | TGRS Research Map | TGRS