Differences in Expression of Epithelial-Mesenchymal Transition (EMT) Induction Genes TGF-Β Pathway Transition in Colorectal Cancer Patients Non-Metastatic and Metastatic
The observed alterations in gene expression related to EMT within the TGF-β/Smad pathway in metastatic colorectal cancer are likely associated with the partial processes of EMT and MET. These alterations may contribute to further metastatic potential and increase the malignancy of the cancer.
Authors
- Arum Linangkung (ORCID: https://orcid.org/0000-0001-5480-0175)
- Hendra Susanto (ORCID: https://orcid.org/0000-0002-3935-4848)
- Adeodatus Yuda Handaya
- Ainul Mardiah (ORCID: https://orcid.org/0000-0002-1205-4909)
- Sri Lestari (ORCID: https://orcid.org/0009-0006-9857-7781)
- Moch. Sholeh (ORCID: https://orcid.org/0009-0006-8061-3078)
Institutions
- State University of Malang (ID)
- University of Brawijaya (ID)
Publication Details
- Journal
- Asian Pacific Journal of Cancer Prevention
- Published
- 2025-09-01
- DOI
- https://doi.org/10.31557/apjcp.2025.26.9.3239
- Citations
- 1
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Universitas Brawijaya
- Universitas Negeri Malang
- Directorate for Biological Sciences