Amygdala and Prefrontal Cortex Maturational Differences in Children and Adolescents With Prenatal Alcohol Exposure
Our findings show altered maturational patterns in amygdala-PFC structures and circuitry among children and adolescents with PAE that suggest reduced brain plasticity. Differences in the developmental timing of these regions may underlie behavioral challenges, such as elevated risk taking and impulsivity, in those with PAE.
Authors
- Bryce Geeraert (ORCID: https://orcid.org/0000-0003-1388-1014)
- Jamie Roeske (ORCID: https://orcid.org/0000-0003-0900-6022)
- Catherine A. Lebel (ORCID: https://orcid.org/0000-0002-0344-4032)
- W. Ben Gibbard (ORCID: https://orcid.org/0000-0002-4091-9332)
- Carly A. McMorris (ORCID: https://orcid.org/0000-0002-5164-6210)
- Keith Owen Yeates (ORCID: https://orcid.org/0000-0001-7680-2892)
- Madison Long (ORCID: https://orcid.org/0000-0002-5660-5899)
- Christina Tortorelli (ORCID: https://orcid.org/0000-0002-6046-3336)
- Jacqueline Pei (ORCID: https://orcid.org/0000-0002-2268-2191)
- Meaghan V. Perdue (ORCID: https://orcid.org/0000-0002-6113-9175)
- Mohammad Ghasoub
- Xiangyu Long (ORCID: https://orcid.org/0000-0001-6451-3313)
Institutions
- University of Alberta (CA)
- University of Calgary (CA)
- Alberta Children's Hospital (CA)
- Mount Royal University (CA)
Publication Details
- Journal
- Biological Psychiatry Cognitive Neuroscience and Neuroimaging
- Published
- 2025-09-13
- DOI
- https://doi.org/10.1016/j.bpsc.2025.08.016
- Citations
- 1
- Primary Topic
- Prenatal Substance Exposure Effects
- Type
- article
- Field-Weighted Citation Impact
- 3.49