Glymphatic function, deep medullary veins, and cognitive impairment in cerebral small vessel disease: A mediation analysis
Both the DMV score and DTI-ALPS index are independent risk factors for cognitive impairment in patients with CSVD. The DTI-ALPS index significantly and partially mediates the relationship between the DMV score and cognitive impairment.
Authors
- Danhong Wu (ORCID: https://orcid.org/0000-0002-1132-6669)
- Tianyao Wang (ORCID: https://orcid.org/0000-0002-9349-8930)
- Hulie Zeng (ORCID: https://orcid.org/0000-0003-0484-836X)
- Meng-Xiang Wang
- Junfei Shen (ORCID: https://orcid.org/0000-0002-8759-7377)
- Xiaoli Yang (ORCID: https://orcid.org/0000-0001-5186-6400)
- Yufan Luo (ORCID: https://orcid.org/0009-0007-3773-4912)
- Wen-Mei Lu
Institutions
- Shanghai Jiao Tong University (CN)
- Fudan University (CN)
- Renji Hospital (CN)
- University of Chicago (US)
Publication Details
- Journal
- Clinical Neurology and Neurosurgery
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1016/j.clineuro.2025.109143
- Citations
- 1
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.91