Implementing a randomization consent to enable Trials within Cohorts in the Swiss HIV Cohort Study – A mixed-methods study
The implementation of the TwiCs design, including the roll-out of a randomization consent in an existing, large-scale cohort, is feasible. The acceptance rate among participants was high.
Authors
- Enos Bernasconi (ORCID: https://orcid.org/0000-0002-9724-8373)
- Elias R Zehnder
- Niklaus Daniel Labhardt (ORCID: https://orcid.org/0000-0003-3599-1791)
- Matthias Briel (ORCID: https://orcid.org/0000-0002-2070-5230)
- Stuart McLennan (ORCID: https://orcid.org/0000-0002-2019-6253)
- Johannes Nemeth (ORCID: https://orcid.org/0000-0003-0683-456X)
- Alain Amstutz (ORCID: https://orcid.org/0000-0003-1716-993X)
- Bernard Surial (ORCID: https://orcid.org/0000-0002-1402-974X)
- Gilles Wandeler (ORCID: https://orcid.org/0000-0002-5278-8763)
- Irène A. Abela (ORCID: https://orcid.org/0000-0002-5566-8628)
- Mohsen Saleh Elalfy (ORCID: https://orcid.org/0000-0002-2809-1552)
- David Jackson‐Perry (ORCID: https://orcid.org/0000-0001-5889-1553)
- Beverley Nickolls
- Marcel Stoeckle (ORCID: https://orcid.org/0000-0002-0088-5078)
- Alexandra Calmy
- Huldrych F. Günthard (ORCID: https://orcid.org/0000-0002-1142-6723)
- Frédérique Chammartin (ORCID: https://orcid.org/0000-0001-8959-2724)
- Sandra E Chaudron (ORCID: https://orcid.org/0000-0002-1385-1854)
- Matthias Cavassini
- Julia Notter (ORCID: https://orcid.org/0000-0003-4821-9995)
- Katharina Kusejko (ORCID: https://orcid.org/0000-0002-4638-1940)
- Dominique L. Braun (ORCID: https://orcid.org/0000-0003-4036-1030)
- Andri Rauch (ORCID: https://orcid.org/0000-0001-5297-6062)
- Ellen Cart‐Richter
- Jochen Steinmann (ORCID: https://orcid.org/0000-0002-0527-8840)
- David Hans-Ulrich Haerry
- Christof Schönenberger
- Julia Hüllstrung
- Samuel Aggeler
Institutions
- University of Geneva (CH)
- University of Bern (CH)
- Queen Mary University of London (GB)
- University of Basel (CH)
- University of Zurich (CH)
- University of St.Gallen (CH)
- University Hospital of Bern (CH)
- Centre Hospitalier Universitaire Vaudois (CH)
- University Hospital of Basel (CH)
- Advisory Board Company (United States) (US)
- Hospital Base (CL)
- Ente Ospedaliero Cantonale (CH)
- University Hospital of Zurich (CH)
- University Hospital of Geneva (CH)
- The Geneva Association (CH)
- Positive Action (US)
- University of Lausanne (CH)
Publication Details
- Journal
- Journal of Clinical Epidemiology
- Published
- 2025-09-13
- DOI
- https://doi.org/10.1016/j.jclinepi.2025.111973
- Primary Topic
- Adolescent and Pediatric Healthcare
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- Freiwillige Akademische Gesellschaft
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung