A genome-wide association study of stroke risk in Asian statin users: evidence from KoGES and UK Biobank

This study identified <i>CDH13</i> as a significant genetic marker associated with stroke risk among Asian statin users. These findings provide the first genome-wide evidence for genetic determinants of stroke susceptibility during statin therapy, supporting the development of personalized prevention strategies in Asian populations.

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Publication Details

Journal
Pharmacogenomics
Published
2025-08-13
DOI
https://doi.org/10.1080/14622416.2025.2558499
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
0.00
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article

A genome-wide association study of stroke risk in Asian statin users: evidence from KoGES and UK Biobank

Hye Sun Gwak, Da Hoon Lee, SeungJin Bae, Jeong Yee et al.
Pharmacogenomics
Lipoproteins and Cardiovascular Health
article

A genome-wide association study of stroke risk in Asian statin users: evidence from KoGES and UK Biobank

Hye Sun Gwak, Da Hoon Lee, SeungJin Bae, Jeong Yee, Yoon‐A Park, Jung Sun Kim, Yubin Song
article en

Abstract

This study identified <i>CDH13</i> as a significant genetic marker associated with stroke risk among Asian statin users. These findings provide the first genome-wide evidence for genetic determinants of stroke susceptibility during statin therapy, supporting the development of personalized prevention strategies in Asian populations.

PharmacogenomicsVol. 26(10-12)
Kangwon National University (KR), Ewha Womans University Medical Center (KR), Sungkyunkwan University (KR)
Openalex Percentile: Top 60%
Lipoproteins and Cardiovascular Health
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