ALA-based photodynamic priming in murine skin increases blood flow and oxygenation
These observations suggest that increasing oxygen and capillary flow combined with increased PpIX production together yield increased PDT efficiency, amplified by this initial light dose from a photodynamic optical priming event occurring 2 h prior to full PDT light delivery.
Authors
- Aleksandra Ilina (ORCID: https://orcid.org/0000-0003-4537-4519)
- Marien Ochoa (ORCID: https://orcid.org/0000-0001-6427-4447)
- Tayyaba G. Hasan (ORCID: https://orcid.org/0000-0003-0871-6057)
- Brian W. Pogue (ORCID: https://orcid.org/0000-0002-9887-670X)
- Xu Cao (ORCID: https://orcid.org/0000-0001-8739-5196)
Institutions
- University of Wisconsin–Madison (US)
- Harvard University (US)
- Massachusetts General Hospital (US)
- Wisconsin Division of Public Health (US)
Publication Details
- Journal
- Journal of Biomedical Optics
- Published
- 2025-09-13
- DOI
- https://doi.org/10.1117/1.jbo.30.s3.s34106
- Primary Topic
- Photodynamic Therapy Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00