Metagenomic Next-Generation Sequencing Reveals Porphyromonas gingivalis in Geriatric Severe Pneumonia Complicated by Empyema: Case Report
This case highlights the clinical utility of mNGS in diagnosing culture-negative pulmonary infections. <i>Porphyromonas gingivalis</i> should be considered a potential pathogen in patients with severe pneumonia and empyema, particularly in those with poor oral hygiene or periodontal disease.
Authors
- Xiaorui Wu
- Jingxuan Qiu
- Guannan Ma (ORCID: https://orcid.org/0000-0002-4108-5296)
- Yi Zhong (ORCID: https://orcid.org/0000-0001-6654-2206)
- Zhirong Wan
- Hui Li (ORCID: https://orcid.org/0000-0003-4759-1779)
- Lei Zhang (ORCID: https://orcid.org/0000-0002-0952-3057)
- Na Guo (ORCID: https://orcid.org/0009-0003-8137-5700)
- Yan Yu
- Yuansheng Gao
Institutions
- Beijing Geriatric Hospital (CN)
- Aerospace Center Hospital (CN)
- Hangzhou Medical College (CN)
- First People's Hospital of Jingzhou (CN)
- Jinzhou Medical University (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/idr.s543666
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00